When to give your dog SILEO

The first dose can be given:

  • Approximately 30–60 minutes before the noise event
  • As soon as your dog shows signs of anxiety or fear related to noise
  • Whenever you hear a noise that causes your dog to be fearful or anxious

It takes about 30 minutes to 1 hour for SILEO to take full effect, and it typically lasts 2 to 3 hours. If the noise continues and the behavioral changes recur, further doses can be given at intervals of 2 hours, up to a total of five times during each noise event, as needed. Do not give another dose of SILEO if your dog appears sedated from the previous dose.

SILEO gel comes preloaded in a multidose oral syringe.

With each dose, SILEO is absorbed into the tissues of the mouth through mucous membranes. It should not be swallowed. If your dog swallows SILEO, allow at least 2 hours before applying the next dose.

Administering SILEO

Videos

How to administer SILEO correctly

Further dosing


Downloads

Dosing chart

Easily determine the appropriate dose by looking up your dog’s weight on this dosing chart, which will indicate the corresponding number of dots your dog should receive.

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Step-by-step dosing instructions

Before using a new syringe, an initial setup is required. Detailed instructions are provided on the package insert.

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Does your dog suffer from noise aversion?

Look for these common behaviors.

Use the Checklist

Important Safety Information: Do not use SILEO in dogs with severe cardiovascular disease, respiratory, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue or in dogs hypersensitive to dexmedetomidine or to any of the excipients. SILEO should not be administered in the presence of preexisting hypotension, hypoxia, or bradycardia. Do not use in dogs sedated from previous dosing. SILEO has not been evaluated in dogs younger than 16 weeks of age or in dogs with dental or gingival disease that could have an effect on the absorption of SILEO. SILEO has not been evaluated for use in breeding, pregnant, or lactating dogs or for aversion behaviors to thunderstorms. Transient pale mucous membranes at the site of application may occur with SILEO use. Other uncommon adverse reactions included emesis, drowsiness or sedation. Handlers should avoid direct exposure of SILEO to their skin, eyes or mouth. Failure to lock the ring-stop on the syringe before dosing SILEO could potentially lead to an accidental overdose. Always review INSTRUCTIONS FOR USE before dispensing and dosing. See full Prescribing Information.

The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

Terms of Use

SILEO® is trademark owned by Orion Corporation Orion Pharma Animal Health. It is manufactured by Orion Corporation and distributed by Zoetis under license from Orion Corporation Orion Pharma Animal Health.
©2017 Zoetis Services LLC. All rights reserved. SIL-00112